Please refer to this user manual:
Yes, it works with other VESC, but still have some difference on the power supply for the lights/horn function.
Ubox(single /dual) : there is 12v power supply port(fan port), which can supply power to the horn/lights that hooked in ewheel ADC adapter
Other VESC: mostly only have 5v output, you need to source 5v horn/lights to work with ewheel adc adapter v2
The old one (Ewheel ADC Adapter) : Mainly supports safe and convinient wiring of brake and throttle with VESC
The new one(Ewheel ADC Adapter V2): It upgrades from above, and have more function (control all lights, horn, brake , throttle , reverse, cruise, 3 speed level.... ) with VESC application.